CentralNotice From Wikipedia, the free encyclopedia Jump to: navigation , search This article relies too much on references to primary sources . Please improve this by adding secondary or tertiary sources . (July 2017) ( Learn how and when to remove this template message ) Some fruit juices and fruits can inhibit enzymes that absorb and metabolize medications. Some fruit juices and fruits can interact with numerous drugs, in many cases causing adverse effects . [1] The effect was first discovered by accident, when a test of drug interactions with alcohol used grapefruit juice to hide the taste of the ethanol. [2] It is still best-studied with grapefruit and grapefruit juice , [1] but similar effects have more recently been seen with some (not all) other citrus fruits . [1] [3] [4] [5] [6] One medical review advises patients to avoid all citrus juices un...