CentralNotice Corpus callosotomy From Wikipedia, the free encyclopedia Jump to: navigation , search "Callosotomy" redirects here. It is not to be confused with Colostomy . Corpus callosotomy is a palliative surgical procedure for the treatment of seizures . As the corpus callosum is critical to the interhemispheric spread of epileptic activity , the procedure seeks to eliminate this pathway. “Efficacy and relatively low permanent morbidity in corpus callosotomy for medically intractable epilepsy have been demonstrated by more than six decades of experience. In addition to seizure reduction, behavior and quality of life may improve.” [ 1 ] The corpus callosum is usually severed in order to stop epileptic seizures. Once the corpus callosum is cut, the brain has much more difficulty sending messages between the hemispheres. Although the corpus callosum is the largest white ...